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Discovering the Power of Grapefruit

Discovering the Power of Grapefruit

Western University

Grapefruit can interact with some types of medication, heightening their potency and increasing the risk of unintentional overdose. We know that today thanks to Lawson Health Research Institute scientist and Western University clinical pharmacologist David Bailey, who discovered the danger in 1991. There are more than 80 drugs on the market affected by grapefruit, including cholesterol medication and some anti-cancer and psychiatric treatments. Bailey’s research prompted the use of medication

Treating Cancer

Engineering & Technology

Treating Cancer

Western University

The world’s first cancer treatment with Cobalt-60 radiation took place at Victoria Hospital in London, Ontario, in 1951. Known as the ‘cobalt bomb,’ it allowed doctors to treat tumours without damaging the skin. Western University’s Dr. Ivan Smith led the therapy’s development and, despite modern advances, the Cobalt-60 unit remains the world’s main radiotherapy machine. Its reliability and cost-effectiveness means it is widely used in developing countries. The cobalt bomb has doubled the

Diagnosing Genetic Disorders

Diagnosing Genetic Disorders

Western University

Dr. Murray Barr co-discovered an inactive chromatin linked to such genetic disorders as Down’s, Klinefelter’s and Turner syndromes. The discovery of the chromatin, known as the Barr Body, led to a simple diagnostic test for certain genetic abnormalities. It also spurred new research into genetically caused diseases. The Western University researcher’s study of sex chromatin bodies helped us better understand and manage certain genetic disorders, including those associated with cognitive problems

Breathing Easier

Breathing Easier

Western University

Premature babies often suffer from respiratory distress. Fred Possmayer of Western University, and Goran Enhorning of the University of Toronto, developed techniques to isolate, purify and sterilize lung surfactant — a substance that allows lungs to expand and breathe — so that it could be used clinically. This preparation, using surfactant extracted from cows’ lungs, is known as bovine lipid extract surfactant. One version of such surfactant, BLES®, is made in London and used by nearly all

Leading the Way

Leading the Way

Western University

Multi-organ transplants are still a challenging procedure, but the first combined liver and bowel transplant in 1988 paved the way. Doctors from the internationally renowned Multi-Organ Transplant Program at Western University’s affiliated University Hospital performed the procedure.Since then, more than 5,000 Canadians have received transplants through London’s extensive hospital network. Today, multiple organ failure is no longer a death sentence.

Treating the Untreatable

Treating the Untreatable

Western University

Neurosurgeon Dr. Charles Drake devised various techniques to repair cerebral aneurysms, just as doctors began working on parts of the brain once thought inoperable. Not only did patients come to him from all over the world, surgeons also made the pilgrimage to learn his technique. The first chair of Western University’s department of clinical neurological sciences, Drake’s work has saved countless patients from hemorrhagic stroke, permanent nerve damage and death.

World’s First Coloured Circulation Coin

World’s First Coloured Circulation Coin

Royal Canadian Mint

In 2004, the Royal Canadian Mint became a trailblazer in the minting industry when it introduced the world’s first coloured circulation coin. The 25-cent coin was produced at the Mint’s Winnipeg plant using a high-speed, computer controlled and precision inkjet process. The coin featured a brilliant red poppy, the symbol of remembrance that pays homage to the brave Canadian men and women who gave their lives in service to this nation, as well as the many veterans who helped to secure our freedom

The Million Dollar Coin

The Million Dollar Coin

Royal Canadian Mint

In 2007 the Royal Canadian Mint produced the world’s first million dollar coin. The 100 kg, 99999 pure gold bullion coin with a $1 million face value was originally conceived as a unique showpiece to promote the Mint’s new line of 99999 pure 1 oz Gold Maple Leaf bullion coins. After several interested buyers came forward, the Mint decided to make a very limited quantity available for sale. To date, five of these majestic gold bullion coins, weighing 3,215 troy ounces each, have been purchased by

A drawing of a CF-105 Arrow. Source: Library and Archives Canada/a111546

William Kuzyk and the CF-105 Arrow

Library and Archives Canada

In 1949, Alberta native William Kuzyk graduated from the University of Toronto with a degree in aeronautical engineering. Upon graduation, he was hired full-time by A.V. Roe Canada Ltd., and he spent the next 10 years working for the cutting-edge aeronautical company. While at A.V. Roe, Kuzyk held a number of positions including Flight Test Engineer, Senior Aerodynamics Engineer and Project Research Engineer. In 1956, he was assigned to work on the CF-105 Arrow (or Avro Arrow). First designed in

C-102 Jetliner during a flight, October 24, 1950. Source: Library and Archives Canada/a067504

The C-102 Jetliner

Library and Archives Canada

On August 10, 1949, A.V. Roe (Avro) Canada Ltd.’s C-102 Jetliner took to the sky. It was the first Canadian passenger jet aircraft to fly in North America. Unfortunately the C-102 Jetliner was 13 days behind the first flight of the de Havilland 106 Comet out of the United Kingdom, making it the second passenger jet aircraft to fly in the world. While the C-102 Jetliner would never carry any paying passengers, it did conduct the world’s first jet airmail flight from Toronto, Ontario, to New York

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