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A Trailblazer in Zoology

Earth & Environment

A Trailblazer in Zoology

Western University

During her long career at Western University, zoologist Helen Battle pioneered the use of fertilized fish eggs to study the effects of pollutants on aquatic life and drinking water, and of carcinogenic substances on cell growth. In 1928, Battle was the first woman in Canada awarded a PhD in Marine Biology, and she was subsequently named one of 19 outstanding women scientists by the national Museum of Natural Science in 1975.

Stroke of Genius

Stroke of Genius

Western University

People at risk of stroke are often prescribed low-doses of Aspirin to stave off heart disease thanks to Dr. Henry Barnett’s research. In the 1970s, he lead a large international clinical trial into Aspirin, showing that any antiplatelet drug could prevent diseases due to arterial thrombosis. Co-founder of Robarts Research Institute at Western University, Barnett would go on to become the world’s leading consultant in stroke care. His research changed the way doctors manage the risk of heart

Blasting Cancer

Blasting Cancer

Western University

The leaves of the Madagascar periwinkle plant, Vinca Rosea, contain a powerful anti-cancer drug. In 1958, chemist Charles Beer and Dr. Robert Noble discovered and isolated it. The Western University researchers’ discovery was serendipitous: Noble received 25 leaves of the plant from his brother, who was also doctor. His brother had in turn received the leaves from one of his patients, who told him periwinkle tea was popular in Jamaica for treating diabetes. Called vinblastine, the drug turned

Discovering the Power of Grapefruit

Discovering the Power of Grapefruit

Western University

Grapefruit can interact with some types of medication, heightening their potency and increasing the risk of unintentional overdose. We know that today thanks to Lawson Health Research Institute scientist and Western University clinical pharmacologist David Bailey, who discovered the danger in 1991. There are more than 80 drugs on the market affected by grapefruit, including cholesterol medication and some anti-cancer and psychiatric treatments. Bailey’s research prompted the use of medication

Treating Cancer

Engineering & Technology

Treating Cancer

Western University

The world’s first cancer treatment with Cobalt-60 radiation took place at Victoria Hospital in London, Ontario, in 1951. Known as the ‘cobalt bomb,’ it allowed doctors to treat tumours without damaging the skin. Western University’s Dr. Ivan Smith led the therapy’s development and, despite modern advances, the Cobalt-60 unit remains the world’s main radiotherapy machine. Its reliability and cost-effectiveness means it is widely used in developing countries. The cobalt bomb has doubled the

Diagnosing Genetic Disorders

Diagnosing Genetic Disorders

Western University

Dr. Murray Barr co-discovered an inactive chromatin linked to such genetic disorders as Down’s, Klinefelter’s and Turner syndromes. The discovery of the chromatin, known as the Barr Body, led to a simple diagnostic test for certain genetic abnormalities. It also spurred new research into genetically caused diseases. The Western University researcher’s study of sex chromatin bodies helped us better understand and manage certain genetic disorders, including those associated with cognitive problems

Breathing Easier

Breathing Easier

Western University

Premature babies often suffer from respiratory distress. Fred Possmayer of Western University, and Goran Enhorning of the University of Toronto, developed techniques to isolate, purify and sterilize lung surfactant — a substance that allows lungs to expand and breathe — so that it could be used clinically. This preparation, using surfactant extracted from cows’ lungs, is known as bovine lipid extract surfactant. One version of such surfactant, BLES®, is made in London and used by nearly all

Leading the Way

Leading the Way

Western University

Multi-organ transplants are still a challenging procedure, but the first combined liver and bowel transplant in 1988 paved the way. Doctors from the internationally renowned Multi-Organ Transplant Program at Western University’s affiliated University Hospital performed the procedure.Since then, more than 5,000 Canadians have received transplants through London’s extensive hospital network. Today, multiple organ failure is no longer a death sentence.

Treating the Untreatable

Treating the Untreatable

Western University

Neurosurgeon Dr. Charles Drake devised various techniques to repair cerebral aneurysms, just as doctors began working on parts of the brain once thought inoperable. Not only did patients come to him from all over the world, surgeons also made the pilgrimage to learn his technique. The first chair of Western University’s department of clinical neurological sciences, Drake’s work has saved countless patients from hemorrhagic stroke, permanent nerve damage and death.

And the Beat Goes On

And the Beat Goes On

National Research Council Canada

For decades, NRC has worked at the very heart of biomedical engineering, a ﬁeld that combines medical expertise with the design and problem solving of engineering. NRC inventions include the world’s ﬁrst cardiac pacemaker and also the ﬁrst to be powered by the human body. These devices – and the newer models they inspired – have saved countless lives around the world. When doctors wondered how to safely restart hearts that stop during surgery, NRC found that a gentle electrical stimulus would do

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